polymyxins

polymyxins
Group of peptide antibiotics produced by Bacillus spp. Molecular weights are around 1000-1200 D and the molecules are cyclic. Act against many Gram negative bacteria, working apparently by increasing membrane permeability.

Dictionary of molecular biology. 2004.

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  • Polymyxin — Polymyxins are antibiotics,cite journal |author=Dixon RA, Chopra I |title=Polymyxin B and polymyxin B nonapeptide alter cytoplasmic membrane permeability in Escherichia coli |journal=J. Antimicrob. Chemother. |volume=18 |issue=5 |pages=557–63… …   Wikipedia

  • drug — drug1 /drug/, n., v., drugged, drugging. n. 1. Pharm. a chemical substance used in the treatment, cure, prevention, or diagnosis of disease or used to otherwise enhance physical or mental well being. 2. (in federal law) a. any substance… …   Universalium

  • Drug — /droog/, n. Zoroastrianism. the cosmic principle of disorder and falsehood. Cf. Asha. [ < Avestan drauga] * * * I Any chemical agent that affects the function of living things. Some, including antibiotics, stimulants, tranquilizers,… …   Universalium

  • polymyxin — /pol ee mik sin/, n. Pharm. any of various polypeptide antibiotics derived from Bacillus polymyxa. [1945 50; < NL polymyx(a) specific epithet ( < Gk poly POLY + mýxa mucus, slime) + IN2] * * * ▪ drug       any of five polypeptide antibiotics… …   Universalium

  • Colistin — Strukturformel Allgemeines Freiname Colistin Andere Namen …   Deutsch Wikipedia

  • Polymyxin E — Strukturformel Allgemeines Freiname Colistin Summenformel …   Deutsch Wikipedia

  • polymyxin — A mixture of antibiotic substances obtained from cultures of Bacillus polymyxa (B. serosporus), an organism found in water and soils and obtainable as a crystalline hydrochloride; all are polypeptides containing various amino acid s and a… …   Medical dictionary

  • Ampicillin — Systematic (IUPAC) name (2S,5R,6R) 6 ([(2R) 2 amino 2 phenylace …   Wikipedia

  • Amoxicillin — Systematic (IUPAC) name (2S,5R,6R) 6 …   Wikipedia

  • Penicillin — For the Japanese band, see Penicillin (band). Penicillin core structure. The R is the variable group. Penicillin (sometimes abbreviated PCN or pen) is a group of antibiotics derived from Penicillium fungi.[1] They include …   Wikipedia

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